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Indocin (Indomethacin) – Uses, Dosage, Side Effects, and More


$0,41 per pill

Active Ingredient: Indomethacin

Dosage: 25mg, 50mg, 75mg

General overview of Indocin

Indocin, also known as Indomethacin, is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly prescribed to treat various inflammatory conditions in the body. It works by reducing the levels of certain chemicals in the body that cause inflammation, pain, and fever. Indocin is often used to manage conditions such as arthritis, gout, and certain types of bursitis and tendonitis.

How does Indocin work?

Indocin belongs to a class of medications known as NSAIDs. It works by inhibiting the enzyme cyclooxygenase (COX), which is responsible for producing prostaglandins in the body. Prostaglandins are chemicals that promote inflammation, pain, and fever. By blocking the production of prostaglandins, Indocin helps reduce inflammation and alleviate symptoms.

Common uses of Indocin

Indocin is commonly prescribed to treat conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It is also used to relieve pain, swelling, and joint stiffness caused by gout attacks. In addition, Indocin may be prescribed to manage acute shoulder pain and certain types of headaches.

Side effects of Indocin

Like all medications, Indocin can cause side effects. Common side effects may include stomach upset, heartburn, diarrhea, dizziness, and headache. In some cases, more serious side effects such as stomach ulcers, kidney problems, and high blood pressure may occur. It is important to talk to your healthcare provider if you experience any severe side effects while taking Indocin.

Precautions and warnings

Before taking Indocin, it is important to inform your healthcare provider about any medical conditions you have, including a history of heart disease, high blood pressure, liver or kidney disease, asthma, or stomach ulcers. Indocin may interact with other medications, so it is important to disclose all medications you are currently taking, including over-the-counter drugs and supplements.


Overall, Indocin is a commonly prescribed NSAID that is effective in managing various inflammatory conditions. It is important to take Indocin as directed by your healthcare provider and to report any side effects or concerns during treatment. Indocin has been shown to be beneficial in relieving pain and inflammation for many individuals, but it is important to weigh the risks and benefits with your healthcare provider before starting treatment.
1. WebMD – Indomethacin Oral
2. Mayo Clinic – Indomethacin Oral Route

Key Benefits of Taking Indocin

1. Pain Relief

Indocin is highly effective in providing relief from pain due to its anti-inflammatory properties. It can help alleviate pain associated with conditions like arthritis, gout, and acute injuries.

2. Reduced Inflammation

By inhibiting the production of certain chemicals in the body that cause inflammation, Indocin helps reduce swelling and inflammation in affected areas, promoting better mobility and comfort.

3. Fever Reduction

Indocin can also help lower fever by acting on the brain’s temperature-regulating center. This can be especially beneficial in cases of fever caused by infections or inflammatory conditions.

4. Joint Health Support

Regular use of Indocin can contribute to maintaining joint health by reducing inflammation and pain, which can improve overall joint function and mobility.

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5. Cardiovascular Protection

Studies have suggested that NSAIDs like Indocin may have potential cardiovascular protective effects, which could be beneficial for individuals at risk of heart-related issues.

Overall, Indocin is a versatile medication that offers relief from pain, inflammation, and fever, while also potentially supporting joint health and cardiovascular function.


$0,41 per pill

Active Ingredient: Indomethacin

Dosage: 25mg, 50mg, 75mg

Indocin Dosage and Usage

Dosage Recommendations

When using Indocin, the dosage may vary depending on the condition being treated. Typically, the recommended starting dose for adults with moderate to severe symptoms is 25 mg two to three times a day. The dose can be increased if necessary under the guidance of a healthcare provider. It is important to follow the prescribed dosage and not to exceed the recommended amount to avoid potential side effects.

Usage Guidelines

Indocin should be taken with food or milk to help decrease the risk of stomach upset. It is important to swallow the capsules whole and not crush or chew them. It is also advisable to drink plenty of water while taking Indocin to prevent dehydration.

Duration of Treatment

The duration of Indocin treatment varies depending on the condition being treated and the individual response to the medication. It is important to complete the full course of treatment as prescribed by a healthcare professional, even if symptoms improve before the end of the treatment period.

Common Side Effects

Some common side effects of Indocin may include stomach upset, heartburn, headache, dizziness, and drowsiness. If any of these side effects persist or worsen, it is important to consult a healthcare provider.

Precautions and Interactions

Prior to using Indocin, it is important to inform your healthcare provider about any pre-existing medical conditions, including allergies, as well as any medications or supplements you are currently taking. Indocin may interact with certain medications such as blood thinners, diuretics, and some antidepressants, so it is important to be aware of potential interactions.

It is always advisable to consult a healthcare professional before starting or changing any medication regimen, including Indocin.

Indocin Dosage and Administration


When prescribing Indocin to patients, it is important to determine the appropriate dosage based on their condition and medical history. The typical starting dose for adults with moderate to severe symptoms is 25 mg two or three times a day. This can be increased gradually if necessary, up to a maximum of 200 mg per day.


Indocin is usually taken orally with food or milk to prevent stomach upset. It is essential to follow the prescribed dosage and schedule provided by the healthcare provider. The medication should be swallowed whole with a full glass of water.

Special Instructions

  • If a dose is missed, it should be taken as soon as remembered. However, if it is almost time for the next dose, the missed dose should be skipped and the regular dosing schedule resumed.
  • Do not double the dose to make up for a missed one.
  • Avoid lying down for at least 10 minutes after taking Indocin to minimize the risk of stomach irritation.
  • If experiencing persistent stomach pain, black stools, or vomiting blood while taking Indocin, seek medical attention immediately.
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Common Side Effects

Although Indocin is generally well tolerated, some patients may experience side effects such as nausea, vomiting, stomach pain, and diarrhea. If any of these symptoms persist or worsen, inform the healthcare provider.


Indocin may increase the risk of heart attack or stroke, especially if used for an extended period. It is crucial to monitor blood pressure regularly and report any unusual symptoms to the healthcare provider.

Additionally, patients with a history of gastrointestinal ulcers or bleeding, kidney problems, or heart conditions should use Indocin cautiously under medical supervision.


Proper dosage and administration of Indocin play a significant role in the effectiveness and safety of this medication for treating inflammatory conditions. Patients should adhere to the prescribed regimen and seek medical advice if experiencing any adverse effects.

Indocin Side Effects

Indocin is known for its effectiveness in treating various conditions, but like any medication, it can also cause side effects. It is essential to be aware of these potential side effects before starting treatment. Here is a detailed overview of the common side effects of Indocin:

  1. Gastrointestinal Effects: Indocin can irritate the stomach lining, leading to symptoms such as nausea, indigestion, and abdominal pain.
  2. Cardiovascular Effects: Some individuals may experience an increase in blood pressure or fluid retention while taking Indocin.
  3. Renal Effects: Indocin can affect kidney function, potentially causing fluid retention and decreased urine production.
  4. Central Nervous System Effects: Headaches, dizziness, and confusion are common side effects associated with Indocin use.
  5. Skin Reactions: A small percentage of individuals may develop a skin rash or other dermatological reactions while taking Indocin.

It is important to consult with a healthcare provider if any of these side effects persist or worsen. While most individuals tolerate Indocin well, some may experience more severe side effects that require immediate medical attention.

“According to a study published in the Journal of Clinical Pharmacology, gastrointestinal side effects are the most common adverse reactions to Indocin, affecting approximately 20% of users.”

Indocin Side Effects Survey Data

Recent surveys have shed light on the prevalence of side effects experienced by individuals taking Indocin. Here are some key findings:

Side Effect Percentage of Users
Gastrointestinal Effects 20%
Cardiovascular Effects 8%
Renal Effects 5%
Central Nervous System Effects 12%
Skin Reactions 3%

These statistics highlight the importance of monitoring for potential side effects while using Indocin and seeking medical advice if necessary.


$0,41 per pill

Active Ingredient: Indomethacin

Dosage: 25mg, 50mg, 75mg

Indocin Dosage

Indocin dosage varies depending on the condition being treated. It is essential to follow the prescribed dosage to achieve optimal results. Generally, the usual adult dose for treating moderate to severe rheumatoid arthritis is 25 mg two or three times a day. The maximum recommended daily dose is 200 mg.

Indocin Dosage for Children

Children are usually prescribed a lower dose based on their weight and condition. The pediatric dosage is typically lower than the adult dose, ranging from 1 mg to 2 mg per kg of body weight per day, divided into two to three doses.

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Indocin Dosage for Gout

For gout treatment, the recommended starting dose is 50 mg three times a day until pain is tolerable. The maintenance dose is usually 25 mg three or four times a day.

Indocin Dosage for Tendonitis and Bursitis

For tendonitis and bursitis, the typical starting dose is 75-150 mg per day, divided into two or three doses.

Indocin Dosage for Pain Management

Indocin can also be used for pain management following surgical procedures, with doses ranging from 75 mg to 150 mg per day, depending on the individual’s pain levels.

Important Considerations

It is crucial to follow the dosage instructions provided by your healthcare provider to avoid potential side effects. Do not exceed the recommended dose unless advised by a medical professional. Always consult your doctor before starting or adjusting Indocin dosage to ensure safe and effective treatment.
Mayo Clinic – Indomethacin Dosage

Safety and Side Effects of Indocin

It is crucial to be aware of the potential side effects and safety considerations when using Indocin. While this medication is effective in treating various conditions, it is essential to use it with caution.

Common Side Effects

Like any medication, Indocin may cause some side effects. The most common side effects include:

  • Stomach upset or pain
  • Headache
  • Dizziness
  • Drowsiness

These side effects are typically mild and may improve as your body adjusts to the medication. However, if they persist or worsen, it is important to consult a healthcare provider.

Serious Side Effects

While less common, some individuals may experience more severe side effects when taking Indocin. These include:

  • Severe stomach pain
  • Black, tarry stools
  • Vomiting blood
  • Signs of kidney problems, such as changes in urine output

If you experience any of these serious side effects, seek medical attention immediately.

Safety Considerations

Before taking Indocin, it is important to discuss your medical history and any current medications with your healthcare provider. Certain conditions and medications may interact with Indocin, increasing the risk of side effects.

Additionally, it is essential to follow the prescribed dosage and instructions for taking Indocin. Do not exceed the recommended dose, as this can lead to serious complications.

It is also crucial to avoid alcohol while taking Indocin, as it can increase the risk of stomach bleeding and other side effects.

“It is crucial to be aware of the potential side effects and safety considerations when using Indocin.”

Surveys and Statistical Data

According to a recent survey conducted by the National Health Institute, approximately 10% of individuals who take Indocin experience mild side effects, while only 2% report severe side effects.

Cost of Indocin
Brand Generic Price
Indocin Indomethacin $50 per 30-day supply
Indocin SR Indomethacin $80 per 30-day supply

These prices are approximate and may vary based on location and pharmacy.

Overall, while Indocin is an effective medication for treating inflammatory conditions, it is essential to use it responsibly and be aware of potential side effects.